Estrogen Alone May Not Suppress Testosterone – By Kristina Fiore, Staff Writer, MedPage Today

Chicago — Simply giving estrogen to male-to-female transgender patients won’t completely suppress testosterone levels, researchers reported here.

In a study from a single-center experience, patients achieved good estrogen levels but only about half reached sufficient testosterone suppression with estradiol with or without a progestin, Matthew Leinung, MD, of Albany Medical College in New York state, reported at the joint meeting of the Endocrine Society and the International Congress on Endocrinology here.